Publications of Thomas Winkler

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Thomas Winkler on Google Scholar

5 Key Publications

Schmitt, H., S. Sell, J. Koch, M. Seefried, S. Sonnewald, C. Daniel, T.H. Winkler, and L. Nitschke. 2016. Siglec-H protects from virus-triggered severe systemic autoimmunity. J Exp Med213:1627-1644.

Sell, S., M. Dietz, A. Schneider, R. Holtappels, M. Mach, and T.H. Winkler. 2015. Control of murine cytomegalovirus infection by gammadelta T cells. PLoS path11:e1004481.

Pötzsch, S., N. Spindler, A.K. Wiegers, T. Fisch, P. Rucker, H. Sticht, N. Grieb, T. Baroti, F. Weisel, T. Stamminger, L. Martin-Parras, M. Mach, and T.H. Winkler. 2011. B cell repertoire analysis identifies new antigenic domains on glycoprotein B of human cytomegalovirus which are target of neutralizing antibodies. PLoS path 7:e1002172.

Weisel, F.J., U.K. Appelt, A.M. Schneider, J.U. Horlitz, N. van Rooijen, H. Korner, M. Mach, and T.H. Winkler. 2010. Unique requirements for reactivation of virus-specific memory B lymphocytes. J Immunol185:4011-4021.

Wellmann, U., M. Letz, M. Herrmann, S. Angermuller, J.R. Kalden, and T.H. Winkler. 2005. The evolution of human anti-double-stranded DNA autoantibodies. Proc Nat Acad Sci USA 102:9258-9263.


Primary Publications(since 2012)

Pfeifle, R., T. Rothe, N. Ipseiz, H.U. Scherer, S. Culemann, U. Harre, J.A. Ackermann, M. Seefried, A. Kleyer, S. Uderhardt, B. Haugg, A.J. Hueber, P. Daum, G.F. Heidkamp, C. Ge, S. Bohm, A. Lux, W. Schuh, I. Magorivska, K.S. Nandakumar, E. Lonnblom, C. Becker, D. Dudziak, M. Wuhrer, Y. Rombouts, C.A. Koeleman, R. Toes, T.H. Winkler, R. Holmdahl, M. Herrmann, S. Bluml, F. Nimmerjahn, G. Schett, and G. Kronke. 2017. Regulation of autoantibody activity by the IL-23-TH17 axis determines the onset of autoimmune disease. Nat Immunol 18:104-113.

Schmitt, H., S. Sell, J. Koch, M. Seefried, S. Sonnewald, C. Daniel, T.H. Winkler, and L. Nitschke. 2016. Siglec-H protects from virus-triggered severe systemic autoimmunity. J Exp Med 213:1627-1644.

Krzyzak, L., C. Seitz, A. Urbat, S. Hutzler, C. Ostalecki, J. Glasner, A. Hiergeist, A. Gessner, T.H. Winkler, A. Steinkasserer, and L. Nitschke. 2016. CD83 Modulates B Cell Activation and Germinal Center Responses. J Immunol196:3581-3594.

Sell, S., M. Dietz, A. Schneider, R. Holtappels, M. Mach, and T.H. Winkler. 2015. Control of murine cytomegalovirus infection by gammadelta T cells. PLoS path 11:e1004481.

Wiegers, A.K., H. Sticht, T.H. Winkler, W.J. Britt, and M. Mach. 2015. Identification of a neutralizing epitope within antigenic domain 5 of glycoprotein B of human cytomegalovirus. J Virol 89:361-372.

Hammersen, J., J. Hou, S. Wunsche, S. Brenner, T. Winkler, and H. Schneider. 2015. A new mouse model of junctional epidermolysis bullosa: the LAMB3 628G>A knockin mouse. Journal invest dermatol 135:921-924.

Brachs, S., A. Turqueti-Neves, M. Stein, D. Reimer, B. Brachvogel, M. Bosl, T. Winkler, D. Voehringer, H.M. Jack, and D. Mielenz. 2014. Swiprosin-1/EFhd2 limits germinal center responses and humoral type 2 immunity. Eur J Immunol 44:3206-19.

Engels, N., L.M. Konig, W. Schulze, D. Radtke, K. Vanshylla, J. Lutz, T.H. Winkler, L. Nitschke, and J. Wienands. 2014. The immunoglobulin tail tyrosine motif upgrades memory-type BCRs by incorporating a Grb2-Btk signalling module. Nat comm 5:5456.

Lutz, J., K. Dittmann, M.R. Bosl, T.H. Winkler, J. Wienands, and N. Engels. 2015. Reactivation of IgG-switched memory B cells by BCR-intrinsic signal amplification promotes IgG antibody production Nat comm 6:8575.

Spindler, N., U. Diestel, J.D. Stump, A.K. Wiegers, T.H. Winkler, H. Sticht, M. Mach, and Y.A. Muller. 2014. Structural basis for the recognition of human cytomegalovirus glycoprotein B by a neutralizing human antibody. PLoS path 10:e1004377.

Hutzler, S., L. Ozgor, Y. Naito-Matsui, K. Klasener, T.H. Winkler, M. Reth, and L. Nitschke. 2014. The ligand-binding domain of Siglec-G is crucial for its selective inhibitory function on B1 cells. J Immunol192:5406-5414.

Simonetti, G., M.T. Bertilaccio, T.V. Rodriguez, B. Apollonio, A. Dagklis, M. Rocchi, A. Innocenzi, S. Casola, T.H. Winkler, L. Nitschke, M. Ponzoni, F. Caligaris-Cappio, and P. Ghia. 2014. SIGLEC-G deficiency increases susceptibility to develop B-cell lymphoproliferative disorders. Haematologica 99:1356-1364.

Schroeder, K., M. Herrmann, and T.H. Winkler. 2013. The role of somatic hypermutation in the generation of pathogenic antibodies in SLE. Autoimmunity 46:121-127.

Song, J., Z. Lokmic, T. Lammermann, J. Rolf, C. Wu, X. Zhang, R. Hallmann, M.J. Hannocks, N. Horn, M.A. Ruegg, A. Sonnenberg, E. Georges-Labouesse, T.H. Winkler, J.F. Kearney, S. Cardell, and L. Sorokin. 2013. Extracellular matrix of secondary lymphoid organs impacts on B-cell fate and survival. Proc Nat Acad Sci USA110: 2915-2924.

Spindler, N., P. Rucker, S. Potzsch, U. Diestel, H. Sticht, L. Martin-Parras, T.H. Winkler, and M. Mach. 2013. Characterization of a discontinuous neutralizing epitope on glycoprotein B of human cytomegalovirus. J Virol 87:8927-8939.

Stein, M.F., S. Lang, T.H. Winkler, A. Deinzer, S. Erber, D.M. Nettelbeck, E. Naschberger, R. Jochmann, M. Sturzl, R.K. Slany, T. Werner, A. Steinkasserer, and I. Knippertz. 2013. Multiple interferon regulatory factor and NF-kappaB sites cooperate in mediating cell-type- and maturation-specific activation of the human CD83 promoter in dendritic cells. Mol Cell Biol33:1331-1344.

Wiede, F., P.D. Fromm, I. Comerford, E. Kara, J. Bannan, W. Schuh, C. Ranasinghe, D. Tarlinton, T. Winkler, S.R. McColl, and H. Korner. 2013. CCR6 is transiently upregulated on B cells after activation and modulates the germinal center reaction in the mouse. Immun Cell Biol91:335-339.

Schietke, R.E., T. Hackenbeck, M. Tran, R. Gunther, B. Klanke, C.L. Warnecke, K.X. Knaup, D. Shukla, C. Rosenberger, R. Koesters, S. Bachmann, P. Betz, G. Schley, J. Schodel, C. Willam, T. Winkler, K. Amann, K.U. Eckardt, P. Maxwell, and M.S. Wiesener. 2012. Renal tubular HIF-2alpha expression requires VHL inactivation and causes fibrosis and cysts. PloS one 7:e31034.